Hoodia gordonii
Hoodia gordonii is a plant native to South Africa which is also often known as Hoodia. In the media, the extract from Hoodia gordonii is advertised as a natural appetite inhibitors. Under the continuous intake of Hoodia extract it to come to a reduction in appetite or to a prolonged feeling of satiety. In the long run this property to a Abnahme des Körpergewichts beitragen.
Studien zum Wirksamkeitsnachweis
In einer tierexperimentellen Untersuchung an Raten wurde unter der Dosierung von 6.25–50 mg/kg eine reduzierte Nahrungsaufnahme und nachfolgend eine Gewichtsreduktion bei den Tieren beobachtet (1). Weitere tierexperimentellen Daten bestätigen diese Ergebnisse (2).
Bisher sind keine Ergebnisse aus Placebo-kontrollierten Studien zur Anwendung von Hoodia gordonii in von Experten begutachteten Zeitschriften publiziert worden. Untersuchungsergebnisse einer Phase-I/II-Untersuchung an 18 Probanden lieferten erste Hinweise, dass die Einnahme über 15 Tage die Gesamtkalorienaufnahme compared with the placebo group reduced (3), resulted in a decrease in body fat, while no adverse effects occurred. These data have been published only as a press release and are not reviewed by experts (3).
Conclusion:
Due to the lack of proof of efficacy in humans at present be no recommendation for the use of Hodia extract the long-term weight reduction.
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Literature: - first van Heerden FR, Marthinus Horak R, Maharaj VJ, Vleggaar R, Senab JV, Gunning PJ. An appetite suppressant from Hoodia species. Phytochemistry. 2007 Oct; 68 (20) :2545-53. Epub 2007 Jul 2
second MacLean DB, Luo LG. Increased ATP content / production in the hypothalamus may be a signal for energy-sensing of satiety: studies of the anorectic mechanism of steroidal glycosides aplant. Brain Res 2004; 1020:1-11. third Lee RA, Balick MJ. Indigenous use of Hoodia gordonii and appetite suppression. Explore (NY). 2007 Jul-Aug;3(4):404-6. Review.
Suchbegriffe: Appetit-Hemmer, Appetitsubpression, Hoodia gordonii, Sättigungseffekt, Wirksamkeit, Wirkung, Sättigungsgefühl, gesättigt
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